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7 05, 2021

Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition

2021-09-10T11:28:32+02:00Maggio 7th, 2021|Pubblicazioni|0 Commenti

We report the implementation of our in silico/synthesis pipeline by targeting the glutathione-dependent enzyme mPGES-1, a valuable macromolecular target in both cancer therapy and inflammation therapy. [...]

28 09, 2020

Development and Validation of a Serum Metabolomic Signature for Endometrial Cancer Screening in Postmenopausal Women

2020-12-14T16:25:34+01:00Settembre 28th, 2020|Pubblicazioni|0 Commenti

Key Points Question  Is combining the blood metabolomic signature of endometrial carcinoma with an ensemble machine learning algorithm a useful system for building a screening test [...]

28 09, 2020

Development and Validation of a Serum Metabolomic Signature for Endometrial Cancer Screening in Postmenopausal Women

2021-04-26T12:51:37+02:00Settembre 28th, 2020|Pubblicazioni|0 Commenti

Abstract Importance  Endometrial carcinoma (EC) is the most commonly diagnosed gynecologic cancer. Its early detection is advisable because 20% of women have advanced disease at the [...]

6 02, 2020

Trifolium Repens Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway

2020-12-22T11:19:25+01:00Febbraio 6th, 2020|Pubblicazioni|0 Commenti

Abstract Some species of clover are reported to have beneficial effects in human diseases. However, little is known about the activity of the forage plant Trifolium [...]

18 10, 2019

Shortage of vital children’s cancer drug stirs fear and outrage

2020-12-11T15:52:43+01:00Ottobre 18th, 2019|Pubblicazioni|0 Commenti

A critical shortage of a chemotherapy used to treat most childhood cancers has galvanized oncologists and parents of sick children. The U.S. medical community has become increasingly [...]

26 08, 2019

Modified drug combination may reduce risk of recurrence for some breast cancer patients

2020-12-11T15:59:44+01:00Agosto 26th, 2019|Pubblicazioni|0 Commenti

Masey Ross, M.D., and Charles Geyer, Jr., M.D. Credit: VCU Massey Cancer Center Oncologists at VCU Massey Cancer Center were invited to co-author [...]

20 08, 2019

Patient preferences explored in multiple myeloma treatment

2020-12-11T16:06:49+01:00Agosto 20th, 2019|Pubblicazioni|0 Commenti

(HealthDay)—An Eastern Cooperative Oncology Group (ECOG) performance status of ≥2 is linked to lower treatment satisfaction in patients with relapsed or refractory multiple myeloma (RRMM), [...]

19 08, 2019

Many clinical trials for new cancer drugs didn’t include any data on race

2020-12-11T16:08:23+01:00Agosto 19th, 2019|Pubblicazioni|0 Commenti

One-third of the clinical trials that led to new cancer drugs approved between 2008 and 2018 didn’t report on the race of trial participants — [...]

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